Product Description

Many of the cells in our body undergo tightly regulated replication to enable growth to occur, and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms; it is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms which underpin the regulation of cell replication, and what is happening at the
molecular level when these fail.

The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, and shows how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.

Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal components of the regulatory machinery through which cell division is controlled, and explains how the failure of these components can lead to the onset of cancer. Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies.

The Molecular Biology of Cancer will prove a valuable resource for any student wishing to gain an insight into the molecular basis of the disease, and possible solutions for its effective control.

Companion Web Site

Features figures from the book available to download, to facilitate lecture preparation, and a web link library to give students easy access to relevant online resources.

Product Details

• Amazon Sales Rank: #390475 in Books
• Published on: 2008-03-13
• Binding: Paperback
• 320 pages

Synopsis
Many of the cells in our body undergo tightly regulated replication to enable growth to occur, and to ensure that damaged or worn out tissues are replaced. Regulation is mediated via many different mechanisms; it is when these mechanisms fail, and regulation is lost, that cancer can result. Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms which underpin the regulation of cell replication, and what is happening at the molecular level when these fail. The second edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics gives a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal components of the regulatory machinery through which cell division is controlled, and explains how the failure of these components can lead to the onset of cancer.Uniquely, within each chapter, students are shown how this molecular knowledge is being applied to develop new targeted therapeutic strategies.

Written with the student learner in mind, the book features a variety of learning features to help students engage with, and master, the concepts presented. The emphasis is not on exhaustive coverage of the field, but on acquiring a solid understanding of the essentials of the subject - and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit. The Molecular Biology of Cancer is an invaluable resource for any student wishing to gain an insight into the molecular basis of the disease, and possible solutions for its effective control. Online Resource Centre The Online Resource Centre features: For registered adopters of the book: * Figures from the book available to download, to facilitate lecture preparation * A testbank of multiple-choice questions, with feedback linked to the book, for use in formative or summative assessment For students: * A web link library, giving easy access to relevant online resources * Hyperlinks to primary literature articles cited in the text

About the Author
Dr Lauren Pecorino, Senior Lecturer and Biochemistry Programme Leader, School of Science, University of Greenwich, UK.

Customer Reviews

Very easy to read and refer to
I am finding this book very good to work with while studying cancer. It gives good diagrams, study tips and helps you to understand the subject overall.

Very clear and interesting book
This book is easy to read and difficult concepts about cancer biology are very well explained with the aid of diagrams and information boxes. Each chapter introduces the basics and contains a useful list of references for further reading.