Product Description

Comprehensive, up–to–date coverage of a revolutionary technique Electrospray ionization mass spectrometry (ESI–MS) has completely changed the way physicists, chemists, and biologists view the study of large molecules. The technique derives detailed information about molecular weights and structures from extremely small sample quantities. ESI–MS can create highly charged forms of very high molecular weight compounds, it is naturally compatible with many types of separation techniques, and it allows noncovalent interactions between molecules in solution to be preserved in the gas phase. But many researchers may not use the technique to its full potential because they are unfamiliar with the different perspectives of its underlying processes, the varied approaches to implementation, and the wide–ranging utility of the technique.

In this book, Richard B. Cole and an assemblage of leading researchers present a single–volume compilation of different approaches to the understanding and exploitation of ESI–MS. This comprehensive guide:
∗ Examines the physical and chemical aspects of the electrospray process and describes the events involved in ion formation as well as the electro–chemical phenomena that are central to charged droplet formation during the process
∗ Explores the coupling of electrospray ionization to various mass spectrometers, including quadrupole, magnetic, time–of–flight, quadrupole ion trap, and Fourier transform ion cyclotron resonance instruments
∗ Describes recent progress in interfacing ESI with solution–based separation techniques, including liquid chromatography and capillary electrophoresis
∗ Charts the rapid development of ESI applications and categorizes them by compound type: peptides and proteins, nucleic acids and their constituents, carbohydrates and lipids, small molecules related to pharmacology and drug metabolism, and organometallics and inorganic compounds

Electrospray Ionization Mass Spectrometry is the indispensable handbook and reference for anyone who wishes to understand, implement, or apply this technique, including researchers in chemistry, metallochemistry, biochemistry, biology, pharmacology, and physics.

Product Details

• Amazon Sales Rank: #806698 in Books
• Published on: 1997-05-08
• Original language: English
• Number of items: 1
• Binding: Hardcover
• 577 pages

From the Back Cover
Comprehensive, up–to–date coverage of a revolutionary technique Electrospray ionization mass spectrometry (ESI–MS) has completely changed the way physicists, chemists, and biologists view the study of large molecules. The technique derives detailed information about molecular weights and structures from extremely small sample quantities. ESI–MS can create highly charged forms of very high molecular weight compounds, it is naturally compatible with many types of separation techniques, and it allows noncovalent interactions between molecules in solution to be preserved in the gas phase. But many researchers may not use the technique to its full potential because they are unfamiliar with the different perspectives of its underlying processes, the varied approaches to implementation, and the wide–ranging utility of the technique.

In this book, Richard B. Cole and an assemblage of leading researchers present a single–volume compilation of different approaches to the understanding and exploitation of ESI–MS. This comprehensive guide:
∗ Examines the physical and chemical aspects of the electrospray process and describes the events involved in ion formation as well as the electro–chemical phenomena that are central to charged droplet formation during the process
∗ Explores the coupling of electrospray ionization to various mass spectrometers, including quadrupole, magnetic, time–of–flight, quadrupole ion trap, and Fourier transform ion cyclotron resonance instruments
∗ Describes recent progress in interfacing ESI with solution–based separation techniques, including liquid chromatography and capillary electrophoresis
∗ Charts the rapid development of ESI applications and categorizes them by compound type: peptides and proteins, nucleic acids and their constituents, carbohydrates and lipids, small molecules related to pharmacology and drug metabolism, and organometallics and inorganic compounds

Electrospray Ionization Mass Spectrometry is the indispensable handbook and reference for anyone who wishes to understand, implement, or apply this technique, including researchers in chemistry, metallochemistry, biochemistry, biology, pharmacology, and physics.

About the Author
RICHARD B. COLE is Associate Professor and Director of the New Orleans Center for Mass Spectrometry Research in the Department of Chemistry at the University of New Orleans. The French Académie des Sciences awarded him the title Professeur de L′Académie during his sabbatical year in France.

Customer Reviews

A very good book, I highly recommend it.
Richard Cole has put together a very good overview on electrospray ionization. The book is a nice compilation of information concerning different aspects of electrospray ionization mass spectrometry.